Product Name: GMP Factory Pharmaceutical Raw Material Miconazole Nitrate CAS: 22832-87-7 Model NO.: USP41 Volatile: Not Volatile State: Solid Type: Analysis reagent Grade Standard: Medicine Grade Certification: GMP Function: Antibiotic and Antimicrobial Agents Trademark: SINOAH Transport Package: 25kg/Drum Specification: USP Origin: China HS Code: 3003101100 Product Description Miconazole nitrateHigh purity Miconazole nitrate 99% powder price with fast deliveryProduct description of Miconazole nitrate:1) Product Name: Miconazole powder //CAS 22832-87-7//Miconazole nitrate2) CAS NO: 22832-87-73) Active ingredients:Miconazole nitrate4) Specification: 99%5) Testing Method:HPLC6) Appearance:White or almost white crystal powderSpecificationStandardAppearanceWhite or almost white crystal powderIdentificationSimilar to standardAppearance of solutionThe solution is clear and not more intensely cloured than reference solutions Y7SolubilityVery slightly soluble in water; soluble in methanol; slightly soluble in alcoholAngle of optical rotation-0.10 ----+0.10Related substancesEach impurity≤0.25%Total imurity≤0.5%Melting point178-182°CLoss on drying≤0.5%Residue on ignition≤0.1%Assay (on dry basis)98.5-102%Functions of Miconazole nitrate:Miconazole nitrate is also called Daknin, he's forest, miconazole, miconazole, miconazole, miconazole, synthetic 1- benzene ethyl imidazole derivatives are imidazole broad-spectrum antifungal agents is acommon drug for the treatment of skin tinea, no hormones, no side effects, the the main active ingredient for miconazole. Miconazole nitrate is rarely used in China now. Its antibacterial spectrum, antibacterial activity and mechanism of action are similar to clotrimazole. It can be used as an alternative to amphotericin Bin the treatment of deep fungal infections. It is suitable for the treatment of systemic and disseminated infections caused by Cryptococcus neoformans and Candida albicans. Oral absorption effect is poor, after local medication mainly stay in the lesion site, absorbed into the body very little. In vivo distribution in the body and the liquid, can penetrate into the joint, and peritoneal inflammation in the vitreous body, but in the sputum, saliva in low concentration of blood cerebrospinal fluid barrier penetration is poor, not easily through the blood-brain barrier. The binding rate of plasma protein was 90%. metabolic inactivation through liver is an inactive metabolite.Miconazole nitrate is an antifungal drug, the drug is Daktarin we are familiar with the commonly used in the treatment of skin tinea, by inhibiting the biosynthesis of the fungal cell membrane components of ergosterol, destroy the structure of cell membrane, the cell membrane permeability increased, resulting in the leakage of intracellular components and inhibit glucose, prevent nutrient intake, eventually fungal cell death, suitable for the treatment of tinea corporis, tinea cruris, tinea manus, tinea pedis, tinea versicolor and fungal paronychia and by yeast (such as Candida) caused by Gram positive bacteria and vaginal infection and secondary infection, external ear infections, bacterial skin infections are effective.
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